Resulting sexual dysfunction can impair quality of life and intimate relationships and discourage patients from taking antidepressants Box 1 , 2. Although most reports have focused on SSRIs, all antidepressant classes have been associated with sexual dysfunction, with prevalence likely influenced by differences in neurotransmitter modulation Table 2. A recent study reported similarly high rates with mirtazapine, but its small sample size limits conclusions about side effect prevalence with this drug. Clomipramine appears to have the highest rates of sexual dysfunction—particularly anorgasmia—probably because it inhibits the serotonin transporter more than do other TCAs.
Antidepressants: Which cause the fewest sexual side effects? - Mayo Clinic
Can Zoloft Cause Erectile Dysfunction?
So I decided to tell him the truth. In my late 50s, my longstanding depression had started to deepen, albeit imperceptibly at first. I continued drinking moderately, a couple of glasses of wine most days of the week, along with a monthly Manhattan. Then two dark and stormy months really shook me up, leaving me in a black hole of despair as depression closed in. The shrink wanted to know whether I was in control of my drinking or my drinking was in control of me. He also suggested I keep a log. More Americans than ever are taking antidepressants.
Managing Antidepressant Sexual Side Effects
Sexual dysfunction which can include problems getting and maintaining an erection, decreased libido, delayed ejaculation, and lack of orgasm is a common side effect of selective serotonin reuptake inhibitors or SSRIs, a class of antidepressant medications that includes Zoloft sertraline. In fact, sexual dysfunction is one of the main reasons that men who are being treated for depression stop taking their medications. A word of caution: Do not abruptly stop taking your Zoloft; this can cause uncomfortable withdrawal symptoms and possible harmful side effects. If you are taking any medication, talk to your pharmacist or physician to see if erectile dysfunction is a known side effect. ED is also associated with smoking , as well as with men who have undergone radiation treatment or surgery for the treatment of prostate cancer.
What if the emotional excess, believed to be essential to creativity, was of the negative and crippling kind? And yet we remain ever so culturally ambivalent about alleviating the anguish of mental illness with the same arsenal we use against physical pain: drugs. In Coming of Age on Zoloft: How Antidepressants Cheered Us Up, Let Us Down, and Changed Who We Are public library , Katherine Sharpe explores the heart of this ambivalence through an intersection of her own experience, conversation with medical and psychiatric experts, and in-depth interviews with forty young adults who grew up on psychopharmaceuticals. Having spent a fair portion of my own life on antidepressants, and having recently resumed treatment, I was instantly fascinated, both as an observer of culture and a living sample size of one.